Off the top of my head:

Yesterday, my wife wanted to use Discord. It was right there in the applications folder. But MacOS couldn't find it. Launching it manually took minutes, for some reason.

We wanted to download a clip using yt_dlp (a Python program). Terminal told us, this would require dev tools, which it doesn't. So we installed Python from python.org instead, which worked. Except, that non-blessed python could not access the internet because of some MacOS "security" feature.

Another security feature requires all apps to be notarized, even the ones I built myself. This used to have a relatively easy workaround (right click, open, accept the risk). Now it needs a terminal command.

I live and work in a multi-lingual environment, and have set up a keyboard shortcut to switch between the German and English keyboard. MacOS does not have a keyboard shortcut for this. But Karabiner can do it, albeit a bit jankily.

Lately, the keyboard layout no longer sticks. It resets to English when I press shift. Sometimes it does work, sometimes it doesn't. This is unrelated to the aforementioned Karabiner shortcut.

The German keyboard layout for MacOS on non-Apple keyboards is insane. So I made my own layout. This is relatively easy, and worked well. Except, every single OS update reinstates Apple's insane layout.

Sometimes my Mac does not wake from sleep. Pressing the power button does nothing. Hitting keyboard keys does nothing. Only a long-press of the power button eventually reboots it. The power button on the Mac Studio is in an insane place of course.

There is still no indication anywhere that the hard drive is getting full.

There is still no simple way to reset the computer to factory conditions.

Gaming is still largely impossible, even though the hardware is very capable.

I have replaced TimeMachine with restic, as TimeMachine keeps resetting itself after a while.

My Linux PC should arrive this week, and will replace the Mac. I've had enough.

It will require wine for two apps, and a VM for two others. At this point, that's a price I'm willing to pay.